Added: Kashena Mcpeak - Date: 26.12.2021 00:03 - Views: 30978 - Clicks: 5509
Brown University researchers outline a method of showing how drugs affect the brain within minutes to hours of being taken. The study outlines strategies for optimizing proton magnetic spectroscopy 1 H-MRS imaging in the minutes to hours following drug ingestion. The work was led by Tara White, assistant professor of behavioral and social sciences research at Brown University, and Meghan Gonsalves, a Ph. The technique described in this latest paper was first applied in a studyled by White, which found a large rise in neocortical glutamate — the major excitatory neurotransmitter in the mammalian brain and nervous system — 2.
What we have is a snapshot in time, which indicates a Brown the drug change in glutamate and other compounds 2. In the new paper, White and Gonsalves provide guidance for researchers, clinicians and drug scientists for the timing of 1 H-MRS imaging in drug administration protocols. They outline strategies for understanding the mechanisms Brown the drug which fast-acting drugs alter emotion, behavior and cognition in humans.
In long-term studies, researchers typically perform imaging acquisition on two groups before and after a treatment — a control group receives an inactive substance while another group is given the treatment. In the new study, however, White and Gonsalves conducted the imaging acquisition during the period in which a fast-acting drug had its immediate effects. The placebo control, which is an inactive substance, was given to the same participants in a time-locked procedure that was identical to the day in which they took the drugs.
As a next step, the researchers will establish a three-pronged research program on brain metabolites that contribute to emotions in healthy adults. White received a Zimmerman Innovation Award last year from the Carney Institute to collect the preliminary data for this project.
The long-term goal, she said, is to build a research program on the neurobiology of human emotion at Brown. Topics Health and Medicine.
Date August 25, Media Contact News Staff [ protected] All News. Share Facebook Twitter Linkedin. Tags Carney Institute Research.
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